abstract：BACKGROUND:A study of the phenotype, activation and adhesive cells factors and cytokines in minor salivary glands in patients with primary Sjögren's syndrome (pSS), secondary Sjögren's syndrome (sSS) and autoimmune diseases (AD) without Sjögren's syndrome. PATIENTS AND METHODS:We have studied the minor salivary glands...

journal_title：Medicina clinica

authors： Tomás S,Coll J,Reth P,Corominas JM

更新日期：1998-11-28 00:00:00

abstract：BACKGROUND:Cytogenetic studies of meningiomas suggest that loss of (or parts of) chromosome 22 is a primary event in the development of these tumors; later on, other chromosomal changes would occur in the caryotypes. All these secondary changes are observed mainly in cases with high clinical aggressivity. However, in a...

journal_title：Medicina clinica

authors： López-Ginés C,Cerdá-Nicolás M,Pérez-Bacete M,Barcia-Salorio JL,Llombart-Bosch A

更新日期：1998-11-21 00:00:00

abstract：BACKGROUND:The aim of the current study is to show the prevalence of atopy in five Spanish areas, and its variability according to area, age and gender. PATIENTS AND METHODS:From a populational based sample of 16,884 individuals aged 20 to 44 years-old, we obtained a randomized 20% subsample (n = 3,310). Participants ...

journal_title：Medicina clinica

authors： Cortés X,Soriano JB,Sánchez-Ramos JL,Azofra J,Almar E,Ramos J

更新日期：1998-11-07 00:00:00

abstract：BACKGROUND:Osteoporosis may be associated with parenchymal hepatopathy and chronic alcoholism. Biochemical studies which are linked with bone metabolism and the bone densitometry may help to understand its physiopathology, before the symptoms appear and its consequences become inevitable. PATIENTS AND METHODS:The stud...

journal_title：Medicina clinica

authors： González Sanz-Agero P,Muñoz Núñez F,Erdozaín Sosa JC,Garrido Cantarero G,Coya Viña J,Sánchez Cabezudo MJ,Martínez Gómez ME

更新日期：1998-10-17 00:00:00

abstract：BACKGROUND:The aim of this study was the assessment of the scientific production and impact on academic and/or hospital promotion ob sabbatical leaves of medical staff from a University hospital. POPULATION AND METHODS:A matched case-control design was used. The Mantel-Haenszel odds ratio (ORMH) and its 95% confidence...

journal_title：Medicina clinica

authors： Asenjo MA,Vernet E,Trilla A,Rodés J,Terés J,Grau J

更新日期：1998-10-03 00:00:00

abstract：BACKGROUND:To evaluate the evolution of the HIV infection in the drug addicts of Madrid. PATIENTS AND METHODS:Data of 2,234 patients that entered for the first time in a Psychiatric Hospital Detoxication Unit of Madrid from October 1985 to december 1996 were recorded. RESULTS:There was a reduction of the percentage o...

journal_title：Medicina clinica

authors： Sopelana P,Carrascosa C,García-Benito P

更新日期：1998-09-12 00:00:00

abstract：BACKGROUND:The empiric antibiotic treatment of intraabdominal infections is in constant evolution. Monotherapy appears to be a desirable goal because of the simplicity of its administration, lack of toxic effects and wide spectrum. PATIENTS AND METHODS:A multicentre, prospective, randomized, open study was carried out...

journal_title：Medicina clinica

authors： Sitges-Serra A,Guirao X,Díaz J,Azanza R,Rodríguez Noriega A,Lizasoaín M,Jover JM,Moreno Azcoita M,Caínzos M

更新日期：1998-06-27 00:00:00

abstract：BACKGROUND:Hip fractures are a major source of mortality and morbidity among the elderly. The aim of the present study is to try to identify predictors of death and of non-deambulation during the period of acute treatment. PATIENTS AND METHODS:Consecutive prospective study of 459 patients older than 65 years admitted ...

journal_title：Medicina clinica

authors： Pagès E,Cuxart A,Iborra J,Olona M,Bermejo B

更新日期：1998-05-23 00:00:00

abstract：BACKGROUND:Diagnosis of mycobacterioses in HIV infected patients is sometimes difficult because of atypical findings. The aim of this study was to assess the utility of gallium scintigraphy in diagnosis of AIDS related mycobacterioses in patients with fever of unknown origin. PATIENTS AND METHODS:We retrospectively re...

journal_title：Medicina clinica

authors： del Val Gómez Martínez M,Gallardo FG,March J,Laguna F

更新日期：1998-05-02 00:00:00

abstract：BACKGROUND:The main goal of the study is to investigate in the Spanish population the value of searching for the Gly380Arg mutation in the transmembrane domain of fibroblast growth factor receptor-3 (FGFR3#) as the basis for the molecular diagnosis of achondroplasia. PATIENTS AND METHODS:Twenty eight achondroplastic p...

journal_title：Medicina clinica

authors： Climent C,Lorda-Sánchez I,Urioste M,Gairi JM,Rodríguez JI,Rubio V

更新日期：1998-04-18 00:00:00

abstract：OBJECTIVES:To investigate the prevalence and risk factors of bacterial vaginosis (BV) in a pregnant population of Barcelona (Spain). MATERIAL AND METHODS:301 pregnant women controlled in the Hospital Clinic i Provincial (HCP) of Barcelona were enrolled in the study. Complete epidemiological information, and vaginal sa...

journal_title：Medicina clinica

authors： Martínez de Tejada B,Coll O,de Flores M,Hillier SL,Landers DV

更新日期：1998-02-21 00:00:00

abstract：BACKGROUND:To determine the frequency and the type of adrenal steroidogenic abnormalities in hirsute women. SUBJECTS AND METHODS:ACTH test was performed during follicular phase in 127 hirsute and 40 normal (control) women. Before ACTH injection we measured in serum by RIA: 17-OH-pregnenolone (17-OH-P5), 17-OH-progeste...

journal_title：Medicina clinica

authors： Salinas Vert I,Audí Parera L,Granada Ybern ML,Lucas Martín A,Pizarro Lozano E,Foz Sala M,Sanmartí Sala A

更新日期：1998-02-14 00:00:00

abstract：BACKGROUND:In recent years there has been a change in the opportunistic diseases incidence in HIV-infected patients. The change could be related to the use antiviral therapy and chemoprophylaxis strategies. The aim of the present study was to evaluate if medical intervention is able to modificate the clinical presentat...

journal_title：Medicina clinica

authors： Delgado J,Pineda JA,Gallardo JA,Leal M,Macías J,Sánchez-Quijano A,Lissen E

更新日期：1998-02-07 00:00:00

abstract：BACKGROUND:We describe the cytogenetic results of 93 patients with myelodysplastic syndromes (MDS). The main object of this report is to analyze the prognostic value of the karyotype in patients with MDS, in relation to the evolution to acute leukemia and the survival time. PATIENTS AND METHODS:Cytogenetic studies wer...

journal_title：Medicina clinica

authors： Solé F,Woessner S,Florensa L,Pérez-Losada A,Acín P,Besses C,García-Eroles L,Sans-Sabrafen J

更新日期：1998-01-31 00:00:00

abstract：BACKGROUND:The aim of the present study was to determine the prevalence and diagnostic usefulness of antineutrophil cytoplasmic antibodies (ANCA) in a Spanish population of patients with inflammatory bowel disease from the province of Tarragona. PATIENTS AND METHODS:One hundred and fifty-six sera obtained from 116 pat...

journal_title：Medicina clinica

authors： Papo M,Quer JC,Pastor RM,García-Pardo G,Olona M,Prats E,Mirapeix E,Rodríguez R,Richart C

更新日期：1998-01-17 00:00:00

abstract：BACKGROUND:It is not settled whether aspirin (ASA) failure may be predicted in stroke and transient ischemic attack (TIA) patients. The risk of ASA failure may be predicted by analyzing the epidemiological traits of patients with stroke or TIA. PATIENTS AND METHODS:We evaluated retrospectively 695 stroke or TIA patien...

journal_title：Medicina clinica

authors： Chamorro A,Blanc R,Ascaso C,Saiz A,Vila N

更新日期：1997-11-01 00:00:00

abstract：BACKGROUND:In 1993 a first study on the scientific production of Spain in 1986-1989 on Biomedicine and Health Sciences, through the Science Citation Index (SCI) was published. The analysis attained the level of centres, with special emphasis in those related to the Health Care System. This paper analyses the period 199...

journal_title：Medicina clinica

authors： Camí J,Zulueta MA,Fernández MT,Bordons M,Gómez I

更新日期：1997-10-18 00:00:00

abstract：BACKGROUND:The aim of this study was to assess the familial aggregation of lipid levels in schoolchildren of Cuenca city, Spain. SUBJECTS AND METHODS:A cross sectional study was made including 307 both sexes schoolchildren 9-12 years old recruited in three schools of Cuenca city, and 346 of their parents. Sociodemogra...

journal_title：Medicina clinica

authors： Martínez Vizcaíno V,Salcedo Aguilar F,Franquelo Gutiérrez R,Jarabo Crespo Y,Muelas Herráiz F,Domínguez Rojas V

更新日期：1997-10-04 00:00:00

abstract：:Spinal cord compression is an infrequent event in patients with non-Hodgkin's lymphomas (NHL) and early diagnosis and therapy are required. The main clinical and histologic characteristics as well as the response to therapy in 10 NHL patients with spinal cord compression diagnosed at a single center in a 7-year period...

journal_title：Medicina clinica

authors： Vela D,Ribera JM,Florensa R,Arellano A,Vaquero M,Batlle M,Flores A,Millá F,Feliu E

更新日期：1997-09-27 00:00:00

abstract：BACKGROUND:Diabetes mellitus is an important cause of mortality and morbidity in western nations with high costs for both patients and health care systems. MATERIAL AND METHODS:Based on the latest epidemiological studies and in combination with Spanish demographic data the direct health care costs of known diabetes me...

journal_title：Medicina clinica

authors： Hart WM,Espinosa C,Rovira J

更新日期：1997-09-13 00:00:00

abstract：BACKGROUND:Strongyloides stercoralis is an endemic nematode in tropical and subtropical regions, but almost unknown in Spain. PATIENTS AND METHODS:In order to know some epidemiological, clinical and analytic features of this infection in our area (La Safor, Valencia), we performed a prospective study for 19 months. Th...

journal_title：Medicina clinica

authors： Cremades Romero MJ,Igual Adell R,Ricart Olmos C,Estellés Piera F,Pastor-Guzmán A,Menéndez Villanueva R

更新日期：1997-07-05 00:00:00

abstract：BACKGROUND:In our society advertising compaigns promote consumption of superfluous foods, such as sweets and snacks, displacing the intake of other basic nutrients. The aim of this study is to assess the intake of these foods by children, their relative contribution to overall macronutrient intake and their effects on ...

journal_title：Medicina clinica

authors： López del Val T,Estivariz CF,Martínez de Icaya P,Jaunsolo MA,del Olmo D,Vázquez Martínez C

更新日期：1997-06-14 00:00:00

abstract：BACKGROUND:We determined the extent to which opportunities for prevention were missed among patients with tuberculosis and the costs derived from the lack of prevention. METHOD:Descriptive study of patients with active tuberculosis were studied in the hospital ward of tuberculosis at the A. Marcide-Novoa Santos Centre...

journal_title：Medicina clinica

authors： García Rodríguez JF,Mariño Callejo A,Lorenzo García MV,de Juan Prego J,Díaz Peromingo JA,Sesema Sánchez P

更新日期：1997-06-07 00:00:00

abstract：BACKGROUND:Loss of heterozygosity (LOH) at 5q21, where the APC/MCC genes reside, is one of the genetic alterations that characterizes lung cancer. The aim of this study was to analyse LOH frequency on chromosome 5q21 in patients with non-small cell lung cancer and its relationship with TNM staging and histological subt...

journal_title：Medicina clinica

authors： Sánchez Céspedes M,López Cabrerizo MP,Moreno I,Ariza A,Monzó M,Rosell R

更新日期：1997-05-31 00:00:00

abstract：BACKGROUND:To know the utilization of the screening mammography among women from 25 to 65 years old in an urban health zone, where there is not an specific screening program for breast cancer. To detect the demographic and risk determinants that are involved in the mammography screening use. SUBJECTS AND METHODS:A sam...

journal_title：Medicina clinica

authors： Simó Miñana J,Gaztambide Ganuza M,Morote Sanchís MV,Palazón Ferrer G,Gálvez Candel J,Salto Sánchez ML,Peñarroja González D,Hernández Aguado I

更新日期：1997-05-24 00:00:00

abstract：BACKGROUND:The aim of this study is to assess the prevalence of Parvovirus B19 infection in a group of patients affected by congenital coagulation disorders and its association with epidemiological aspects. PATIENTS AND METHODS:We have analyzed a group of 50 patients (median age 28) diagnosed with haemophilia or any o...

journal_title：Medicina clinica

authors： Aguilar Franco C,Lucía Cuesta JF,Ferrer Torres J,Omeñaca Teres M

更新日期：1997-05-03 00:00:00

abstract：:Atherosclerotic renovascular disease is a common entity, particularly in persons older than 50 years of age and especially in those patients with other evidence of atherosclerotic vascular disease. The illness clearly progresses in some patients, and progression rate appears to be highly variable. Taken into account t...

journal_title：Medicina clinica

authors： de Sequera P,Abad J,Albalate M,Torres M,Vázquez A,Sierra MP,Casado S

更新日期：1997-04-12 00:00:00

abstract：BACKGROUND:Outbreaks of nosocomial infection by methicillin resistent Staphylococcus aureus (MRSA) are a problem in many hospitals with the control measures to be adopted being controversial. An outbreak of MRSA in a 550-bed university hospital is herein described and the impact of the adopted control measures on the e...

journal_title：Medicina clinica

authors： Sopena N,Sabrià M,Pedro-Botet ML,Giménez M,Esteve M,Caraballo M,Mesalles E

更新日期：1997-03-22 00:00:00

abstract：BACKGROUND:We have not found any study assessing the sensitivity of different frequencies of nosocomial infection surveillance (NIS). The objective of this study is to contribute to the ascertainment of the frequency of the NIS surveillance in surgical patients, where NIS has shown to be most efficient. METHODS:A pros...

journal_title：Medicina clinica

authors： Delgado-Rodríguez M,Medina Cuadros M,Martínez Gallego G,Fariñas Alvarez C,Sillero Arenas M

更新日期：1997-02-08 00:00:00

abstract：BACKGROUND:The aim of this study was to evaluate the morbidity and mortality attributable to smoking. MATERIAL AND METHODS:A transversal study was performed in a reference population of residents of the province of Granada (Spain). The number of deaths in 1985, the number of patients admitted to public hospitals in 19...

journal_title：Medicina clinica

authors： Rodríguez Tapioles R,Bueno Cavanillas A,Pueyos Sánchez A,Espigares García M,Martínez González MA,Gálvez Vargas R

更新日期：1997-02-01 00:00:00

abstract：BACKGROUND:To determine carboxyhemoglobin levels and to investigate carbon monoxide poisoning risk in children. PATIENTS AND METHODS:We determine carboxyhemoglobin blood levels by cooximetry in 65 children, between 15 days and 15 years attended in a pediatric emergency section. We analyze carbon monoxide risk factors ...

journal_title：Medicina clinica

authors： Vázquez P,López-Herce J,Galarón P,Merello Godino C

更新日期：1997-01-11 00:00:00

abstract：BACKGROUND:Erythema induratum of Bazin (BEI), is included in the group of cutaneous granulomatous lobulillar panniculitis. The aethiopathogenic association between EI and tuberculosis can not rely on the clinicohistological features of these panniculitis and M. tuberculosis has never been isolated from BEI lesions. Det...

journal_title：Medicina clinica

authors： Margall N,Baselga E,Coll P,Barnadas M,Sánchez F,de Moragas JM,Prats G

更新日期：1996-11-30 00:00:00

abstract：BACKGROUND:Data on drug consumption obtained from emergency room clinical records have been used for various epidemiological purposes. However the validity and reliability of these data remain unknown. This paper assesses the reliability and validity of an Emergency Room Toxicological Register (HMR) which has collected...

journal_title：Medicina clinica

authors： Pérez K,Domingo-Salvany A,Garcés JM,Hartnoll RL

更新日期：1996-11-23 00:00:00

abstract：BACKGROUND:To analyze the relationship between length of hospitalary stay and early readmission rate. To assess the hypothesis that those admissions with the lowest length of stay are associated with higher early readmission rate. PATIENTS AND METHODS:Retrospective study of 35,902 hospital admissions. A single admissi...

journal_title：Medicina clinica

authors： Castells X,Riu M,Sáez M

更新日期：1996-11-02 00:00:00

abstract：BACKGROUND:The generation of the use of informed consent forms makes necessary to grant their legibility for patients. Up to now, we didn't have in Spain a suitable yardstick for evaluating the reading levels. METHODS:A sample of 10 texts of diverse procedence, 8 journals and 16 informed consent forms were collected. ...

journal_title：Medicina clinica

authors： Simón Lorda P,Barrio Cantalejo IM,Concheiro Carro L

更新日期：1996-10-26 00:00:00

abstract：BACKGROUND:The aim of this study was to analyze the influence of age on the clinical and biological features as well as the results of treatment in 41 adult patients with acute lymphoblastic leukemia (ALL). PATIENTS AND METHODS:The patients diagnosed with ALL from January 1989 to October 1995 in a single center were s...

journal_title：Medicina clinica

authors： Ribera JM,Granada I,Navarro JT,Vela D,Juncá J,Flores A,Millá F,Feliu E

更新日期：1996-10-05 00:00:00

abstract：BACKGROUND:The aim of this study was to analyze the predictive factors of IDDM in first degree relatives of IDDM patients. SUBJECTS AND METHODS:From 1992 to 1994, 1,053 first degree relatives were screened for measuring islet cell antibodies (ICA) by indirect immunofluorescence (iFl). In all ICA positive subjects, bet...

journal_title：Medicina clinica

authors： Rodríguez-Villar C,Conget I,Esmatjes E,Levy I,Calvet J,Figuerola D,Bergua M,Gutiérrez A,Miralles J,Millán M,Peig M,Gomis R

更新日期：1996-09-28 00:00:00

abstract：BACKGROUND:To know current hepatitis B (HBV) and hepatitis A (HAV) infection status among a group of health sciences students during 1990-1993 period. SUBJECTS AND METHODS: SUBJECTS:1,734 health sciences students during 1990-1991, 1992-1993 and 1993-1994 academic years. MAIN OUTCOME MEASURES:demographic variables, v...

journal_title：Medicina clinica

authors： Bayas JM,Bruguera M,Vilella A,Carbó JM,Vidal J,Navarro G,Nebot X,Prat A,Salleras L

更新日期：1996-09-14 00:00:00

abstract：BACKGROUND:To check the possible usefulness in studying DNA in dried blood spots taken on filter paper blotters for newborn identification. It set out to establish: 1. The validity of the method for analysis; 2. The validity of all stored samples (such as those kept in clinical records); 3. Guarantee of non-intrusion i...

journal_title：Medicina clinica

authors： Rodríguez-Alarcón Gómez J,Martińez de Pancorbo Gómez M,Santillana Ferrer L,Castro Espido A,Melchor Maros JC,Linares Uribe MA,Fernández-Llebrez del Rey L,Aranguren Dúo G

更新日期：1996-06-22 00:00:00

abstract：BACKGROUND:The incidence of typhoid fever in Spain from January 1982 to December 1993 was studied with the aim of analyzing how the disease has evolved over these years and predict its future behavior in order to facilitate prevention by the public health care organizations and centers. MATERIAL AND METHODS:The Box-Je...

journal_title：Medicina clinica

authors： Ríos M,García JM,Cubedo M,Pérez D

更新日期：1996-05-11 00:00:00